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ey0017.1-7 | Hypopituitarism: Disease Modeling and New Discoveries | ESPEYB17

1.7. Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators

C Huisman , H Cho , O Brock , SJ Lim , SM Youn , Y Park , S Kim , SK Lee , A Delogu , JW Lee

To read the full abstract: Nat Commun. 2019 Aug 16;10(1):3696. doi: 10.1038/s41467-019-11667-y. PMID: 31420539.The hypothalamic arcuate nucleus (ARC) controls crucial physiological processes, such as growth, reproduction and energy homeostasis. However, it is unknown how ARC neurons gain their unique cellular identities and what are their developmental relationships. Here, the authors i...

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ey0015.1-1 | New mechanisms | ESPEYB15

1.1 Female sexual behavior in mice is controlled by kisspeptin neurons

V Hellier , O Brock , M Candlish , E Desroziers , M Aoki , C Mayer , R Piet , A Herbison , WH Colledge , V Prevot , U Boehm , J Bakker

To read the full abstract: Nat Commun 2018;9.400Pheromones play a crucial role to identify potential mates and sexual motivation in mice. These molecules are detected by a specialized circuit which initiates in the nasal septum and then relies on GnRH neurons in the hypothalamus in a sex-dependent manner. Female pheromones induce LH/testosterone release in male mice whereas male pheromones i...

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ESPE Yearbook of Paediatric Endocrinology

1.7. Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators

1.1 Female sexual behavior in mice is controlled by kisspeptin neurons

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